David Sinclair is a gerontologist (scientist who studies aging) from the University of New South Wales. He has been leading a team of researchers attempting to slow or stop the degenerative effects of aging in mice.
Sinclair was optimistic about their most recently tested compound, but even he was shocked by how successful it was:
“I’ve been studying aging at the molecular level now for nearly 20 years and I didn’t think I’d see a day when aging could be reversed. I thought we’d be lucky to slow it down a little bit. The mice had more energy, their muscles were as though they’d be exercising and it was able to mimic the benefits of diet and exercise just within a week. We think that should be able to keep people healthier for longer and keep them from getting diseases of aging.”
The compound toned the mice’s muscles as if they had been exercising, reduced inflammation (one of the biggest factors in age-related health issues) and drastically reduced insulin resistance, which naturally increases as we grow older.
The researchers compared the effect observed in the mice to a 60-year old person suddenly having the muscle tone and energy of a person in their 20s. More impressively, these results were seen in only one week.
One of the keys to the success of the anti-aging compound was that it raised levels of nicotinamide adenine dinucleotide. This substance is naturally produced in our bodies, and decreases with age. It decreases more slowly, however, in people who maintain a healthy diet and exercise regularly.
Sinclair hopes to begin testing the compound on humans soon, but says he must raise more funding before he can set an official start date for these human trials.
Read the full story from The Guardian Liberty Voice here.
Also, check out David Sinclair’s awesome TED talk on this topic from last year: